- January 22, 1856 - Alfred Denis Godley, classical scholar and writer, is born in Ashfield, Co. Cavan
- January 25, 1627 - Robert Boyle, physicist, chemist and alchemist, is born in Lismore, Co. Waterford
- January 27, 1975 - Mother Mary Martin, founder of the Medical Missionaries of Mary, dies in Drogheda
- February 25, 1841 - John Philip Holland - Irish inventor and developer of the modern submarine, born
- March 16, 1828 - Patrick Cleburne, American Civil War Confederate General, is born in Cobh, Co. Cork
- March 25, 1831 - Arthur Kavanagh, politician and progressive landlord, is born in Borris, Co. Carlow
- April 10, 1512 - King James V was born at Linlithgow Palace, son of King James IV and Margaret Tudor
- April 12, 1654 - The Ordinance of Union comes into effect, uniting Ireland and Scotland with England
- April 21, 1875 - Michael, The ORahilly, Irish Volunteers leader, is born in Ballylongford, Co. Kerry
- May 12, 1725 - The Black Watch regiment was commissioned under General Wade to police the Highlands.
- June 3, 1878 - Sinéad de Valera, née Flanagan; teacher and writer, is born in Balbriggan, Co. Dublin
- June 6, 1798 - General Needham reaches Arklow in Co. Wexford and immediately begins digging trenches
- June 6, 1871 - Joseph Shanahan, missionary bishop in Africa, is born near Templederry, Co. Tipperary
- June 10, 1939 - Sir Jackie Stewart, three-times world motor racing champion, born in Dunbartonshire.
- July 27, 1663 - The Navigation Act restricts Irish trade with colonies as well as exports to England
- August 15, 1856 - Birth at Holytown of John Keir Hardie, coal miner and founder of the Labour Party.
- September 8, 1830 - Thomas Nicholas Burke, Dominican friar, preacher and lecturer, is born in Galway
- October 18, 1881 - A “no rents manifesto” is issued by the Land League under the guidance of Parnell
- October 27, 1728 - James Cook, circum-navigator of the globe, born to Scottish parents in Yorkshire.
- October 31, 1888 - Pneumatic bicycle tires were patented by inventor John Boyd Dunlop from Ayrshire.
- November 1, 1798 - Sir Benjamin Guinness, owner of the Guinness brewery from 1855, is born in Dublin
- November 14, 1918 - Seumas O'Kelly, playwright, novelist , short story writer , and journalist, dies
- November 28, 1727 - William Connolly is unanimously re-elected Speaker of the Irish House of Commons